The survey of septal heart defects in Down syndrome patients at Imam Reza and Imam Ali hospitals in Kermanshah, 2002-2011‎

AUTHORS

Zahra Jalili 1 , Mohammad Reza‏ ‏ Salahshoor 2 , Vahid‏ ‏Mohammadi ‎ 3 , Cyrus Jalili 4 , *

1 Department of Pediatric‏ ‏Cardiology, Imam Ali‏ ‏Hospital , Kermanshah University of Medical‏ ‏Sciences, Kermanshah‎, Iran

2 Fertility and Infertility‏ ‏Research Center,‎‏ ‏Kermanshah University of‏ ‏Medical Sciences, Kermanshah‎, Andorra

3 School of Medicine‏ ‏Kermanshah University of‏ ‏Medical Sciences, Kermanshah‎, Iran

4 Fertility and Infertility‏ ‏Research Center,‎‏ ‏Kermanshah University of‏ ‏Medical Sciences, Kermanshah‎, Iran

How to Cite: Jalili Z , Salahshoor M R ‏, ‏Mohammadi ‎ V, Jalili C . The survey of septal heart defects in Down syndrome patients at Imam Reza and Imam Ali hospitals in Kermanshah, 2002-2011‎, J Clin Res Paramed Sci. 2013 ; 2(3):e82261.

ARTICLE INFORMATION

Journal of Clinical Research in Paramedical Sciences: 2 (3); e82261
Published Online: November 13, 2013
Article Type: Research Article
Received: April 13, 2013
Accepted: October 06, 2013

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Abstract

Background: Down syndrome is the most common chromosomal abnormality due to 21 trisomy that usually is accompany with congenital heart diseases. About fifty present of children with Down syndrome have heart defects. This study was designed for the aim of abundance percents of septal heart defects in children with Down syndrome at Imam Reza and Imam Ali hospitals in Kermanshah.

Methods: This study was down for 89 patients with Down syndrome. Data’s were achieved by echocardiography results and files of patients admitted at Imam Reza and Imam Ali hospitals during 2002 – 2011 in Kermanshah. Data’s were included septal defects, age, sex, history of mother,s abortion, pregnant mother,s age, patients mortality, parent,s relative and history of family diseases.

Results: Ventricular and atrial septal defect respectively were 15 patients [9 girls (10.1%) and 6 boys (6.74%)] and 11 cases [6 girls (6.74%) and 5 boys (5.6%)]. History of parents heart diseases was 22 [13 mothers (14.6%) and 9 fathers (10.11%)], 10 patients (11.2%) were dead and parent,s relative were 53 cases (59.6%). History of mother,s abortion was 17 (19.3%). The most incidence was in mother,s age (between 21-30 age years old) include 35 cases (39.32%).

Conclusion: Abundance percents of ventricular septal defects were more than atrial septal defects and were related to sex. On the other hand these defects were more in children of mothers with family relative, low ages (under twenties and also between 21-30 years age old), history of heart diseases and also history of abortions.

Keywords

septal defects of heart chambers Down syndrome children of Kermanshah

© 2013, Journal of Clinical Research in Paramedical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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