Antibacterial effect of six plant extracts on some pathogenic bacteria

AUTHORS

Maryam Abolghazi 1 , Ramin Abiri 2 , Mohammad Bagher Majnooni 1 , Badieh Fallahi 3 , Mehran Babanejad‎ 4 , *

1 Students Research committee, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran

2 Department of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

3 Students Research committee, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran

4

How to Cite: Abolghazi M , Abiri R , Bagher Majnooni M , Fallahi B , Babanejad‎ M. Antibacterial effect of six plant extracts on some pathogenic bacteria, J Clin Res Paramed Sci. 2013 ; 2(3):e83582.

ARTICLE INFORMATION

Journal of Clinical Research in Paramedical Sciences: 2 (3); e83582
Published Online: November 18, 2013
Article Type: Research Article
Received: April 16, 2013
Accepted: October 17, 2013

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Abstract

Introduction: According to side effects of chemical drugs, recently much attention has been paid to plants as a drug. The present study aimed to determine the antibacterial effect of six plant extracts on some pathogenic bacteria.
Materials and Methods: In an experimental study, at first the six plant extracts including Cinnamon, Turmeric, Thyme, Peganum harmala, Citrus aurantium and Achillea were prepared. Next, with regard to the minimum Inhibitory concentration (MIC) and standardized broth micro dilution method concentrations of each extract successively 62 to 12000 μg/ml prepared and then a 0.5 McFarland unit concentration of eight bacteria including standard Staphylococcus aurous (standard strain), Pseudomonas aeruginosa, Staphylococcus aurous, Enterococus Faecium, Escherichia coli, Salmonella typhi, Shigella dysenteriae and Klebsiella Pneumonia was obtained. The prepared compound was diluted back to 1 in a thousand.
Results: All the extracts were able to inhibit the growth of all bacteria. In general, Peganum harmala and Turmeric were the most inhibitor so that their MIC against shigella dysenteriae was 62 and 125µg/ml, respectively. Cinnamon was the third against shigella dysenteriae and the standard Staphylococcus aurous strains at a concentration of 1000 µg/ml. Achillea, Citrus aurantium and Thyme had not a considerable inhibitory against all bacteria.
Conclusions: In general, Peganum harmala, Turmeric and Cinnamon had a higher antibacterial activity and can be used as a food preservative and a drug compound for treatment.

Keywords

Antibacterial Plant extract Pathogenic bacteria

© 2013, Journal of Clinical Research in Paramedical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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